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Article | IMSEAR | ID: sea-214648

ABSTRACT

Nephropathy is one of the serious diabetic complications and haemodialysis the common modality employed generally aimed to correct the altered crystalloids as well as to remove accumulated nitrogenous waste products. But it rarely corrects the vascular lipid levels, hence increasing the thrust of dyslipidaemia and dyslipidaemia induced cardiovascular complications in these patients. A study was planned to assess the cardiovascular risk factors, Cardiac Risk Ratio, Atherogenic Index of plasma and Atherogenic Coefficient in these patients to evaluate the cardiovascular risk.METHODSPatients of type 2 diabetes suffering from diabetic nephropathy undergoing haemodialysis at Subbaiah Institute of Medical Sciences, Shivamogga, and its affiliated hospitals in the age group of 30-60 years were randomly selected. A heparinised blood sample was collected after obtaining a written consent. Plasma lipid profile, Cardiac Risk Ratio, Atherogenic index of plasma and Atherogenic Coefficient were estimated. Aged matched non-diabetic subjects and type 2 diabetic patients without renal complications served as normal controls and diabetic controls respectively.RESULTSLevels of FPG, TC, TAG, HDLC, LDLC, VLDLC, CRR, AIP and AC were significantly elevated in patients of diabetic nephropathy.CONCLUSIONSPatients of diabetic nephropathy undergoing regular haemodialysis must be screened frequently for cardiovascular complications.

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